Search results for "Treatment evaluation"

showing 4 items of 4 documents

Replacement therapy for bleeding episodes in factor VII deficiency: A prospective evaluation

2013

Patients with inherited factor VII (FVII) deficiency display different clinical phenotypes requiring ad hoc management. This study evaluated treatments for spontaneous and traumatic bleeding using data from the Seven Treatment Evaluation Registry (STER). One-hundred one bleeds were analysed in 75 patients (41 females; FVII coagulant activity <1-20%). Bleeds were grouped as haemarthroses (n=30), muscle/subcutaneous haematomas (n=16), epistaxis (n=12), gum bleeding (n=13), menorrhagia (n=16), central nervous system (CNS; n=9), gastrointestinal (GI; n=2) and other (n=3). Of 93 evaluable episodes, 76 were treated with recombinant, activated FVII (rFVIIa), eight with fresh frozen plasma (FFP), s…

MaleRegistrieTime FactorsFactor VII Deficiency030204 cardiovascular system & hematologyReplacement therapyProspective evaluationchemistry.chemical_compound0302 clinical medicineMedicineProspective StudiesRegistriesYoung adultProspective cohort studyFactor VII deficiencyChildHematologyFactor VIIHematologyMiddle AgedRecombinant ProteinBlood Coagulation FactorsRecombinant ProteinsTreatment OutcomeCoagulantChild PreschoolFemaleBlood Coagulation FactorHumanAdultmedicine.medical_specialtyAdolescentTime FactorHemorrhageBlood Component TransfusionFactor VIIaBleeds; Factor VII deficiency; Replacement therapy; Adolescent; Adult; Aged; Blood Coagulation Factors; Child; Child Preschool; Coagulants; Drug Administration Schedule; Factor VII Deficiency; Factor VIIa; Female; Hemorrhage; Humans; Infant; Infant Newborn; Male; Middle Aged; Prospective Studies; Recombinant Proteins; Registries; Time Factors; Treatment Outcome; Young Adult; Blood Component Transfusion; HematologyDrug Administration Schedule03 medical and health sciencesYoung AdultInternal medicineHumansAgedBleeding episodesbusiness.industryCoagulantsInfant NewbornInfantSurgeryProspective StudieTreatment evaluationchemistryBleedbusiness030215 immunology
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Prophylaxis in congenital factor VII deficiency: indications, efficacy and safety. Results from the Seven Treatment Evaluation Registry (STER)

2013

WOS: 000319897700018

RegistrieSevere bleedingAdultMalePediatricsmedicine.medical_specialtyTime FactorsTime FactorAdolescentFactor VII DeficiencyPROPHYLAXIS FACTOR VII DEFICIENCYFactor VIIachemistry.chemical_compoundPlasmaYoung AdultMedicineHumansRegistriesYoung adultFactor VII deficiencyChildFactor VIIbusiness.industryInfantHematologyRecombinant ProteinFactor VIIMiddle Agedmedicine.diseaseThrombosisRecombinant ProteinsClinical trialTreatment OutcomechemistryTreatment evaluationWeekly doseChild PreschoolFemaleOriginal Articles and Brief ReportsbusinessHuman
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A fully automatic 2D segmentation method for uterine fibroid in MRgFUS treatment evaluation

2015

PurposeMagnetic Resonance guided Focused UltraSound (MRgFUS) represents a non-invasive surgical approach that uses thermal ablation to treat uterine fibroids. After the MRgFUS treatment, an operator must manually segment the treated fibroid areas to evaluate the NonPerfused Volume (NPV). This manual approach is operator-dependent, introducing issues of result reproducibility, which could lead to errors in the subsequent follow-up phase. Moreover, manual segmentation is time-consuming, and can have a negative impact on the optimization of both machine-time and operator-time. MethodTo address these issues, in this paper a novel fully automatic method based on the unsupervised Fuzzy C-Means cl…

medicine.medical_specialtyDatabases FactualUterine fibroidsComputer scienceAdaptive thresholdingImage ProcessingAdaptive thresholding; Automatic segmentation; Fuzzy C-Means clustering; MRgFUS treatment; Uterine fibroids; Female; Humans; Image Processing Computer-Assisted; Leiomyoma; Radiography; Algorithms; Databases Factual; Magnetic Resonance Imaging; Ultrasonography InterventionalHealth InformaticsFuzzy logicDatabasesComputer-AssistedImage Processing Computer-AssistedmedicineHumansSegmentationCluster analysisFactualUltrasonography InterventionalUltrasonographySettore ING-INF/05 - Sistemi Di Elaborazione Delle InformazioniInterventionalLeiomyomaPixelbusiness.industryPattern recognitionmedicine.diseaseMagnetic Resonance ImagingFuzzy C-Means clusteringComputer Science ApplicationsSurgeryRadiographyTreatment evaluationMRgFUS treatmentFully automaticFemaleManual segmentationArtificial intelligenceAutomatic segmentationAdaptive thresholding Automatic segmentation Fuzzy C-Means clustering MRgFUS treatment Uterine fibroidsbusinessAlgorithmsUterine fibroids
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A Semi-automatic Multi-seed Region-Growing Approach for Uterine Fibroids Segmentation in MRgFUS Treatment

2013

Fibroids are benign tumors growing in the uterus. Most of fibroids do not require treatment unless they are causing symptoms. Traditional surgery treatments, like myomectomy and hysterectomy, are very invasive therapeutic approaches which not always preserves reproductive potential of the woman. MRgFUS, performed with Insightec ExAblate 2100 equipment, is a new and noninvasive technique for uterine fibroids treatment, not requiring hospitalization and recovery time for patients. An initial assessment of MRgFUS treatment is made by computing the ablated volume of uterine fibroid. In this paper a semi-automatic approach, based on region-growing segmentation technique, is proposed. The impleme…

medicine.medical_specialtyHysterectomyMRgFUSUterine fibroidsComputer scienceExAblatemedicine.medical_treatmentmedicine.diseasefemale genital diseases and pregnancy complicationsSegmentationTreatment evaluationArtificial IntelligenceRegion growingMDSSmedicineRegion-growingReproductive potential3D volume reconstructionUterine fibroidSegmentationSemi automaticRadiologySoftware2013 Seventh International Conference on Complex, Intelligent, and Software Intensive Systems
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